The trial

Clinical trial of an investigational compound that is being developed for the treatment of neurological disorders (such as Parkinson’s disease).

  • You are a healthy male or female.
  • You are at least 18 and no more than 55 years old.
  • Your Body Mass Index (BMI) is at least 18.0 and at most 32.0 kg/m2. 
  • Both non-smokers and light smokers (maximum of 5 cigarettes per day) are allowed to participate in this clinical trial. During your stay in our research facility you are not allowed to smoke.

Note: 

  • You cannot participate in the trial if you have participated in another clinical trial in the 30 days prior to the first compound administration in this clinical trial (counting from the follow-up visit of the previous study). For some study compounds this can be 90 days. This will be discussed during your telephone screening.
  • To determine if you are suitable to participate in this trial, you will undergo a medical screening. Depending on availability, this can be performed in Groningen or in Utrecht.

As a female you can only participate if you meet one of the following conditions:

  • You have passed the menopause (no periods for at least 12 months);
  • You have been sterilized.

As a male you can only participate if you meet one of the following conditions:

  • You are using a condom in combination with an additional contraception method used by your female partner;
  • You have been sterilized or your female partner is sterilized or has passed the menopause (no periods for at least 12 months);
  • You are not sexually active according to your lifestyle;
  • You are only sexually active with a partner of the same sex.

Period

For group 1, 2 or 3 of part A the trial consists of 1 period during which you will stay in the research facility in Groningen (location van Swietenlaan 6) for 3 days (2 nights) followed by 10 short visits. The follow-up visit will take place during your last short visit. 

Note: You must be available for all dates to be able to participate in this clinical trial. 

Compensation

  • For participation in group 4, 5 or 6, you will receive a gross compensation of € 5074,-.

Travel expenses will be reimbursed based on the distance traveled (€ 0.21 net per kilometer) with a minimum of € 13 and a maximum of € 176.40 (840 kilometers) per round trip, regardless of the mode of transportation.

Wallet

Want to participate in this trial?

You can! Fill in your information in this application form. The clinical trial centre responsible will then contact you about your participation.

I want to participate

Attention: Smoking volunteers may smoke 5 cigarettes per day at most.